C9357

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl)

≥96% (HPLC), suitable for western blotting and enzyme immunoassays

• 別名: XJ735
• 実験式（ヒル表記法）: C₂₃H₃₂N₈O₇
• CAS番号: 153381-95-4
• 分子量: 532.55
• MDL番号: MFCD11046000
• UNSPSCコード: 12352209
• PubChem Substance ID: 329775202
• NACRES: NA.26

特性

• product name: Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl), ≥96% (HPLC)
• 品質水準: 200
• アッセイ: ≥96% (HPLC)
• 形状: powder
• テクニック: enzyme immunoassay: suitable; western blot: suitable
• 色: white
• UniProtアクセッション番号: P01303
• 保管温度: −20°C
• SMILES記法: C[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2
• InChI: 1S/C23H32N8O7/c1-12-19(35)31-15(6-3-7-26-23(24)25)21(37)28-11-17(32)30-16(9-18(33)34)22(38)27-10-13-4-2-5-14(8-13)20(36)29-12/h2,4-5,8,12,15-16H,3,6-7,9-11H2,1H3,(H,27,38)(H,28,37)(H,29,36)(H,30,32)(H,31,35)(H,33,34)(H4,24,25,26)/t12-,15-,16-/m0/s1
• InChI Key: HRASXYOWQQTBAQ-RCBQFDQVSA-N
• 遺伝子情報: human ... NPY(4852)

詳細

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

生物化学的／生理学的作用

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin αvβ3. XJ735 is used to study the role of integrin αvβ3 in cell-matrix interactions and processes.

Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)