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C1671

Chlorprothixene hydrochloride

別名:

2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride

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この商品について

実験式(ヒル表記法):
C18H18ClNS · HCl
CAS番号:
分子量:
352.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
229-289-3
MDL number:
Form:
powder


form

powder

storage temp.

2-8°C

SMILES string

Cl.CN(C)CC\C=C1\c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;

InChI key

YWKRLOSRDGPEJR-KIUKIJHYSA-N

Gene Information

General description

Chlorprothixene is a neuroleptic drug, which belongs to thioxanthene group. It has anticholinergic effects. Chlorprothixene might be associated with obstructive jaundice and parkinsonism. It is used to treat psychosis.

Application

Chlorprothixene hydrochloride has been used to study its exposure effects on learning and memory of rats.

Biochem/physiol Actions

D2 dopamine receptor antagonist; blocks a subset of GABAA receptors in rat cortex that is also blocked by clozapine; thioxanthine antipsychotic.

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当該品目
C1915000P4670E5406
form

powder

form

-

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Gene Information

human ... DRD2(1813), DRD3(1814), HTR2A(3356), HTR2C(3358)

Gene Information

human ... ABCB1(5243), ADRB1(153), ADRB2(154), ADRB3(155), CYP1A2(1544), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Gene Information

human ... CHRM1(1128)


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

保管分類

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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