ABK0004
RituBridge ELISA Kit
ログインで組織・契約価格をご覧ください。
サイズを選択してください
表示を変更する
この商品について
NACRES:
NA.32
UNSPSC Code:
41116158
Species reactivity:
human (Human IgG)
Storage temp.:
2-8°C
Shipped in:
wet ice
antibody form
IgG fraction of antiserum
species reactivity
human (Human IgG)
technique(s)
ELISA: suitable
shipped in
wet ice
storage temp.
2-8°C
General description
A Protein Conformational Array (PCA) in a sandwich ELISA format where the plate is coated with a panel of antibodies raised against peptides derived from the full length protein sequence of Rituximab. Taken individually, each of these antibodies is strongly antigenic to the peptide sequence that was used in its production. However, when these peptides are incorporated into a full length correctly folded protein, the antigenicity of many of them is masked by the three dimensional structure of the protein and only a limited number of the antibodies respond. The result is a histogram which can be likened to a ‘fingerprint′ for correctly folded Rituximab. For a Rituxan Biosimilar, if the protein is correctly folded and glycosylated, the ‘fingerprint′ will match that of Rituximab. If it is not correctly folded, previously masked peptide sequences will be exposed and will be recognized by the antibody made to that exposed sequence. In this way, changes in the ‘fingerprint′ generated by the ELISA will point out differences between the Biosimilar and authentic Rituximab.
Application
For research use only. Not for use in diagnostic procedures.
注意喚起語
Warning
ハザードコード
Hazard Classifications
Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
一体何が起きているの？
WGK 1
保管分類
10 - Combustible liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Please refer to KIT Component information
pdsc
Please refer to KIT Component information
prtr
Please refer to KIT Component information
fsl
Please refer to KIT Component information
ishl_indicated
Please refer to KIT Component information
ishl_notified
Please refer to KIT Component information
cart
キットコンポーネントの情報を参照してください
jan