PHR1594

Methacycline hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• 別名: Methacycline hydrochloride, 6-Demethyl-6-deoxy-6-methyleneoxytetracycline monohydrochloride
• 実験式（ヒル表記法）: C₂₂H₂₂N₂O₈ · HCl
• CAS番号: 3963-95-9
• 分子量: 478.88
• Beilstein: 5470951
• EC Number: 223-568-3
• MDL番号: MFCD04972012
• UNSPSCコード: 41116107
• PubChem Substance ID: 329823498
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to BP 911; traceable to USP 1397006
• APIファミリー: methacycline
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: neat
• 保管温度: -10 to -25°C
• SMILES記法: Cl[H].[H][C@@]12[C@@H](O)[C@]3([H])C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
• InChI: 1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1
• InChI Key: VZQARNDJLLWXGL-CCHMMTNSSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methacycline hydrochloride is one of the tetracycline antibiotics effective against a broad-spectrum of Gram-positive and Gram-negative bacteria. It is formed as an intermediate during the preparation of oxytetracycline. Its antibacterial activity is higher than that of tetracycline and oxytetracycline. It finds applications in human and veterinary medications as well as feed additives.

アプリケーション

Methacycline hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and electroanalytical techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

アナリシスノート

このような2次標準は、入手可能な場合にはUSP、EP、BPの1次標準にマルチトレーサビリティを提供します。

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

脚注

To see an example of a Certificate of Analysis for this material enter LRAC2077 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable