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Merck

91018

Supelco

(S)-NIFE

for chiral derivatization, ≥98.0%

別名:

N-(4-Nitrophenoxycarbonyl)-L-phenylalanine 2-methoxyethyl ester

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About This Item

実験式(ヒル表記法):
C19H20N2O7
CAS番号:
分子量:
388.37
MDL番号:
UNSPSCコード:
12000000
PubChem Substance ID:

グレード

for chiral derivatization

アッセイ

≥98.0% (HPLC)
≥98.0%

フォーム

powder

SMILES記法

COCCOC(=O)[C@H](Cc1ccccc1)NC(=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C19H20N2O7/c1-26-11-12-27-18(22)17(13-14-5-3-2-4-6-14)20-19(23)28-16-9-7-15(8-10-16)21(24)25/h2-10,17H,11-13H2,1H3,(H,20,23)/t17-/m0/s1

InChI Key

ZSOUYIBYVUBOGT-KRWDZBQOSA-N

その他情報

New chiral derivatizing agent for amino acid analysis by HPLC; derivatization of secondary amino acids

保管分類コード

13 - Non Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


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Sonika Sethi et al.
Biomedical chromatography : BMC, 34(1), e4730-e4730 (2019-10-28)
LC separation of biologically and pharmaceutically important enantiomers (from racemic or non-racemic mixtures) remains a subject of importance. The present review article deals with the liquid chromatographic enantioseparation of chiral selective serotonin reuptake inhibitors (SSRIs), namely citalopram, paroxetine, sertraline and
E. Olajos et al.
Chromatographia, 54, 77-77 (2001)
A. Peter et al.
Chromatographia, 52, 821-821 (2000)
Antal Péter et al.
Journal of chromatography. A, 948(1-2), 283-294 (2003-07-02)
A new chiral derivatizing agent, (S)-N-(4-nitrophenoxycarbonyl)phenylalanine methoxyethyl ester, (S)-NIFE, was applied for the high-performance liquid chromatographic separation of enantiomers of 19 unnatural secondary amino acids: proline, pipecolic acid analogues, piperazine-2-carboxylic acid, morpholine-3-carboxylic acid, thiomorpholine-3-carboxylic acid and analogues containing the 1,2,3,4-tetrahydroisoquinoline
Cecilia Barbas-Bernardos et al.
Journal of chromatography. A, 1611, 460598-460598 (2019-10-20)
In the nutrition field, there is a lack of understanding about the impact that dietary chiral composition may have on health, especially regarding cooked meals. Chiral amino acids (AAs) are naturally present in food and their proportion may vary quite

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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