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Merck

03557

Sigma-Aldrich

ポリエチレングリコール

tested according to Ph. Eur., 35,000

別名:

マクロゴール 35,000, PEG

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About This Item

化学式:
H(OCH2CH2)nOH
CAS番号:
MDL番号:
UNSPSCコード:
12161900
PubChem Substance ID:
NACRES:
NA.21

認証

tested according to Ph. Eur.

品質水準

形状

powder

分子量

~35000

溶解性

aliphatic hydrocarbons: slightly soluble
organic solvents: soluble

アプリケーション

pharmaceutical (small molecule)

SMILES記法

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI Key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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アプリケーション

Poly (ethylene glycol) can be used as a test compound utilized in the overproduction and purification of recombinant Lactobacillus reuteri LrNDT. It can also be used for concentrating the mutants with lower secretion levels used in ELISAs for the quantitation of shgp190 and of the LIF/shgp190 complexes.

生物化学的/生理学的作用

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.

調製ノート

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

281.5 °F - closed cup

引火点(℃)

138.6 °C - closed cup

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

03557-BULK:
03557-1KG:
03557-VAR:


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Jesús Fernández-Lucas et al.
Applied and environmental microbiology, 76(5), 1462-1470 (2010-01-06)
A novel type II nucleoside 2'-deoxyribosyltransferase from Lactobacillus reuteri (LrNDT) has been cloned and overexpressed in Escherichia coli. The recombinant LrNDT has been structural and functionally characterized. Sedimentation equilibrium analysis revealed a homohexameric molecule of 114 kDa. Circular dichroism studies
Juliette Bitard et al.
The Journal of biological chemistry, 278(18), 16253-16261 (2003-02-26)
The leukemia inhibitory factor (LIF) receptor comprises the low affinity binding chain gp190 and the high affinity converter gp130. The ectodomain of gp190 is among the most complex in the hematopoietin receptor family, because it contains two typical cytokine receptor
J L Cleland et al.
The Journal of biological chemistry, 267(19), 13327-13334 (1992-07-05)
Polyethylene glycol (PEG) inhibited aggregation during refolding of bovine carbonic anhydrase B (CAB) through the formation of a nonassociating PEG-intermediate complex. Stoichiometric concentrations of PEG were required for complete recovery of active protein during refolding at aggregating conditions. For example
J L Cleland et al.
Bio/technology (Nature Publishing Company), 10(9), 1013-1019 (1992-09-01)
Previous studies on the refolding of recombinant bovine carbonic anhydrase B (CAB) indicated that polyethylene glycol (PEG) significantly enhanced the recovery of active protein by reducing aggregation. To further test the ability of PEG to enhance refolding, three recombinant human
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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