SKINMAG-50K

MILLIPLEX^® Human Skin Magnetic Bead Panel - Immune Response Multiplex Assay

The analytes available for this multiplex kit are: Cortisol, Fibronectin, Involucrin, Keratin-6, Keratin-1,10, HSA.

• UNSPSCコード: 12161503
• eCl@ss: 32161000

特性

• 化学種の反応性: human
• メーカー／製品名: Milliplex^®
• assay range: accuracy: 96-107%; sensitivity: 0.25 ng/mL; (Involucrin); sensitivity: 0.85 ng/mL; (Cortisol); sensitivity: 2.05 ng/mL; (HSA); standard curve range: 0.055-40 ng/mL; (Involucrin); standard curve range: 0.55-400 ng/mL; (Cortisol); standard curve range: 2.74-2000 ng/mL; (HSA); inter-assay cv: <15%; intra-assay cv: <10%
• テクニック: multiplexing: suitable
• 検出方法: fluorometric (Luminex xMAP)
• 輸送温度: wet ice

詳細

詳細

Skin is the largest organ in the body, with such diverse functions as mechanical barrier, thermoregulation, vitamin D synthesis, vitamin B folate protection, fluid homeostasis, sensation, and innate immunity. The skin responds to damage by up-regulating repair mechanisms and causing skin hyperproliferation. Consequently, analysis of biochemical components from the stratum corneum (SC) can be used to evaluate skin irritation, SC integrity and structure and inflammatory changes in human skin.

The MILLIPLEX^® Human Skin Panel is a 5-plex kit to be used for the simultaneous quantification of any or all of the following analytes in skin, skin tape extract or skin cell
culture samples: cortisol, keratin-6, involucrin, keratin-1,10, and human serum albumin (HSA).

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Immune Response

特異性

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

アプリケーション

• Analytes: Cortisol, Human Serum Albumin (HSA), Involucrin, Keratin-6, Keratin-1,10
• Recommended Sample type: Skin, skin tape extract, skin cell culture samples
• Assay Run Time: One day or Overnight
• Research Category: Inflammation & Immunology

特徴および利点

Design your multiplex kit by choosing available analytes within this panel.

保管および安定性

Recommended storage for kit components is 2 - 8°C.

アナリシスノート

Fibronectin, Keratin-6, and Keratin 1, 10 are lot specific see product insert.

その他情報

Please contact Technical Service for linearity of dilution.

Sensitivity: Fibronectin, Keratin-6, and Keratin 1, 10 are lot specific see product insert.

法的情報

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS06,GHS08,GHS05,GHS09
• シグナルワード: Danger
• 危険有害性情報: H302 + H332,H311,H317,H318,H360D,H373,H411
• 注意書き: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1 - STOT RE 2
• ターゲットの組織: Respiratory Tract
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects