MABE270

Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1

clone 19E2.1, from mouse

• 別名: Signal transducer and activator of transcription 6, IL-4 Stat
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 19E2.1, monoclonal
• 化学種の反応性: human, mouse
• テクニック: flow cytometry: suitable; western blot: suitable
• アイソタイプ: IgG2aκ
• NCBIアクセッション番号: NP_001171549
• UniProtアクセッション番号: P42226
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pTyr641)
• 遺伝子情報: human ... STAT6(6778)

詳細

詳細

Signal transducer and activator of transcription 6 (STAT6) transduces signals from extracellular cytokines during adaptive immunity and has recently been found to be important in the innate immune response to viral infection. STAT6 is also involved in the attenuation of the Th1 and Th17 in the nephritogenic immune response. The consequence of STAT6 activity has been associated with the pathogenesis of autoimmune disease and has been found to be actively imported to the nucleus.

特異性

This antibody recognizes STAT6 phosphorylated at (Tyr641).

免疫原

Epitope: Phosphorylated (Tyr641)

KLH-conjugated linear peptide corresponding to human STAT6 phosphorylated at (Tyr641).

アプリケーション

Research Category
エピジェネティクス及び核内機能分子

Research Sub Category
転写因子

Anti-phospho STAT6 (Tyr641) Antibody, clone 19E2.1 is a mouse monoclonal antibody for detection of phospho STAT6 (Tyr641) also known as Signal transducer & activator of transcription 6, IL-4 Stat & has been validated in WB, FC.

Flow Cytometry Analysis: 2 µg/mL from a representative lot detected STAT6 in human peripheral blood leukocytes.

品質

Evaluated by Western Blot in NIH/3T3 cell lysates treated and untreated with PDGF.

Western Blot Analysis: 0.5 µg/mL of this antibody detected STAT6 on 10 µg of PDGF untreated and treated NIH/3T3 cell lysates.

ターゲットの説明

~165 kDa observed

物理的形状

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
NIH/3T3 cell lysates treated and untreated with PDGF

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable