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ABC963

Anti-phospho Mitofusin2 Antibody (Ser442)

Name: Anti-phospho Mitofusin2 Antibody (Ser442)
Brand: MM

別名:

Mitofusin-2|Transmembrane GTPase MFN2

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この商品について

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Clone:

polyclonal

Species reactivity:

human

Application:

WB, inhibition assay

Citations:

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特性

biological source

rabbit

Quality Segment

300

clone

polyclonal

species reactivity

human

technique(s)

inhibition assay: suitable (peptide), western blot: suitable

詳細

General description

Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.

Immunogen

KLH-conjugated linear peptide corresponding to human phospho Mitofusin2 (Ser442).

Application

Anti-phospho Mitofusin2 Antibody (Ser442) is an antibody against phospho Mitofusin2 (Ser442) for use in Western Blotting, Peptide Inhibition Assay.

Analysis Note

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 1.0 ug/mL of this antibody detected phospho Mitofusin2 (Ser442) in 10 ug of SH-SY5Y cell lysate.

Other Notes

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

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当該品目	M6319	M6444	ABS79
Sigma-Aldrich ABC963 Anti-phospho Mitofusin2 Antibody (Ser442)	Sigma-Aldrich M6319 Anti-Mitofusin-2 (N-Terminal) antibody produced in rabbit	Sigma-Aldrich M6444 Anti-Mitofusin 2 antibody produced in rabbit	Sigma-Aldrich ABS79 Anti-phospho-mTOR (Ser2159) Antibody
species reactivity human	species reactivity mouse, human, rat	species reactivity human, mouse, rat	species reactivity human
clone polyclonal	clone polyclonal	clone polyclonal	clone polyclonal
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
technique(s) inhibition assay: suitable (peptide), western blot: suitable	technique(s) immunoprecipitation (IP): 5-10 μg using HeLa human epitheloid carcinoma cell lysate, indirect immunofluorescence: 20-30 μg/mL using differentiated mouse C2 cells, western blot (chemiluminescent): 0.5-1 μg/mL using extracts of rat or mouse brain mitochondria	technique(s) immunoprecipitation (IP): 5-10 μg using HeLa human epitheloid carcinoma cell lysate, western blot (chemiluminescent): 0.5-1 μg/mL using extract of mouse and rat brain mitochondria	technique(s) dot blot: suitable, inhibition assay: suitable (peptide), western blot: suitable
Quality Level 300	Quality Level 200	Quality Level 200	Quality Level 100

保管分類

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c