539149

Proteasome Substrate VI, Fluorogenic

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome.

• 別名: Proteasome Substrate VI, Fluorogenic, Z-ARR-AMC, 2HCl
• 実験式（ヒル表記法）: C₃₃H₄₄N₁₀O₇ · 2HCl
• CAS番号: 90468-18-1
• 分子量: 765.69
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white to off-white
• 溶解性: DMSO: 200 mg/mL; 80% acetic acid: 50 mg/mL; methanol: soluble
• 蛍光検出: λ_ex ~380 nm; λ_em ~460 nm
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A fluorogenic substrate for assaying trypsin-like activity of proteasome. Also serves as a substrate for cathepsin B. Excitation max: 360-380 nm; emission max.: 430-460 nm.

A fluorogenic substrate probe useful for assaying trypsin-like activity of proteasome. Also reported to be a specific substrate for cathepsin B.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Proteasome

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

シーケンス

Z-Ala-Arg-Arg-AMC

物理的形状

Supplied as hydrochloride salt.

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C

その他情報

Geier, E., et al. 1999. Science283, 978.
Dick, T.P., et al. 1998. J. Biol. Chem. 273, 25637.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable