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Merck

454582

Sigma-Aldrich

Anti-NMDAR 2B (984-1104) Rabbit pAb

lyophilized, Calbiochem®

別名:

Anti-N-Methyl-D-Aspartate Receptor 2B-Subunit

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.43

由来生物

rabbit

品質水準

抗体製品の状態

purified antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

lyophilized

含まれません

preservative

化学種の反応性

rat, fish, mouse, human

メーカー/製品名

Calbiochem®

保管条件

OK to freeze

アイソタイプ

IgG

輸送温度

ambient

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

Immunoaffinty purified rabbit polyclonal antibody. Recognizes the ~180 kDa NMDAR2B subunit of the NMDA receptor.
Recognizes the ~180 kDa NMDA receptor NR2B subunit.
This Anti-NMDAR 2B (984-1104) Rabbit pAb is validated for use in Immunoblotting, Immunohistochemistry, Immunoprecipitation for the detection of NMDAR 2B (984-1104).

免疫原

Rat Brain
a recombinant fusion protein consisting of amino acids 984-1104 of rat brain NMDAR 2B-subunit

アプリケーション

Immunoblotting (1:1000)

Immunohistochemistry (1:1000-1:2000)

Immunoprecipitation (see comments)

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from 5 mM ammonium bicarbonate.

再構成

Reconstitute in 50 µl PBS. Following reconstitution, aliquot and freeze (-20°C). Avoid freeze thaw cycles of reconstituted solution.

その他情報

Does not cross-react with NMDAR2A or NMDAR2C. Please refer to the certificate of analysis for lot-specific immunoprecipitation volume. Variables associated with assay conditions will dictate the proper working dilution.
Wang, Y.H., et al. 1995. J. Neurochem.65, 176.
Petralia, R.S., et al. 1994. J. Neurosci.14, 6102.
Ishii, T., et al. 1993. J. Biol. Chem.268, 2836.
Monyer, H., et al. 1992. Nature256, 1217.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

454582-UG:
454582-10UG:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Ainhoa Plaza-Zabala et al.
Neuroscience letters, 557 Pt B, 101-106 (2013-11-23)
Hypocretin peptides are critical for the effects of cocaine on excitatory synaptic strength in the ventral tegmental area (VTA). However, little is known about their role in cocaine-induced synaptic plasticity in the nucleus accumbens (NAc). First, we tested whether hypocretin-1
Carrie R Ferrario et al.
PloS one, 7(8), e40898-e40898 (2012-08-08)
We previously showed that the time-dependent intensification ("incubation") of cue-induced cocaine seeking after withdrawal from extended-access cocaine self-administration is accompanied by accumulation of Ca(2+)-permeable AMPA receptors (CP-AMPARs) in the rat nucleus accumbens (NAc). These results suggest an enduring change in
Leonardo Santana Novaes et al.
Translational psychiatry, 11(1), 18-18 (2021-01-09)
The persistence of anxiety and the deficit of fear memory extinction are both phenomena related to the symptoms of a trauma-related disorder, such as post-traumatic stress disorder (PTSD). Recently we have shown that single acute restraint stress (2 h) in rats
Carrie R Ferrario et al.
Neuroscience letters, 490(3), 180-184 (2010-12-25)
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.
Daniela Bonini et al.
Neural plasticity, 2016, 7267865-7267865 (2016-03-12)
Clinical studies on patients with stress-related neuropsychiatric disorders reported functional and morphological changes in brain areas where glutamatergic transmission is predominant, including frontal and prefrontal areas. In line with this evidence, several preclinical works suggest that glutamate receptors are targets

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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