324905

Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem

A cell-permeable antitumor antibiotic.

• 別名: Epirubicin Hydrochloride - CAS 56390-09-1 - Calbiochem, 4ʹ-Epidoxorubicin, HCl
• 実験式（ヒル表記法）: C₂₇H₂₉NO₁₁ · xHCl
• CAS番号: 56390-09-1
• 分子量: 543.52 (free base basis)
• MDL番号: MFCD00941448
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 色: orange-red
• 溶解性: water: 1 mg/mL
• 輸送温度: ambient
• 保管温度: 2-8°C
• InChI: 1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22-,27-;/m0./s1
• InChI Key: MWWSFMDVAYGXBV-FGBSZODSSA-N

詳細

詳細

A cell-permeable, antitumor antibiotic. A stereoisomer of doxorubicin that exhibits reduced cardiotoxicity. Its antitumor actions are mediated by targeting topoisomerase II.

This product has been discontinued.

生物化学的／生理学的作用

Cell permeable: yes

Primary Target
Antitumor antibiotic

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

再構成

Following reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Luck, H.J., et al. 1996. Semin. Oncol.23, 33.
Sandri, M.I., et al. 1996. Br. J. Cancer73, 1518.
Boddy, A.V., et al. 1995. Eur. J. Cancer31A, 69.
Pouna, P., et al. 1995. Cancer. Chemother. Pharmacol.35, 257.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302,H340,H350,H360
• 注意書き: P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable