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詳細
Rabbit polyclonal antibody purified by DEAE anion exchange chromatography. Recognizes C-reactive protein.
Recognizes C-reactive protein. Does not exhibit cross-reactivity against normal human serum.
免疫原
purified, human CRP
アプリケーション
ELISA (see application references)
Immunoblotting (0.1 µg/ml,see application references)
Immunoprecipitation (see comments)
Radioimmunoassay (see comments)
Immunoblotting (0.1 µg/ml,see application references)
Immunoprecipitation (see comments)
Radioimmunoassay (see comments)
包装
Please refer to vial label for lot-specific concentration.
警告
Toxicity: Standard Handling (A)
物理的形状
In 100 mM NaCl, 15 mM phosphate buffer, pH 7.2-7.4.
その他情報
Exhibits a single precipitin line against CRP control serum. Does not exhibit cross-reactivity against normal human serum. The optimal dilution for RIA and immunoprecipitation should be determined for each sample type. Antibody should be titrated for optimal results in individual systems.
Ridker, P.M., et al. 1997. N. Engl. J. Med.336, 973.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
235752-ML:
235752-1ML:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Donald N Ngwa et al.
Frontiers in immunology, 11, 586669-586669 (2020-10-30)
C-reactive protein (CRP) binds to several species of bacterial pathogens including Streptococcus pneumoniae. Experiments in mice have revealed that one of the functions of CRP is to protect against pneumococcal infection by binding to pneumococci and activating the complement system.
Maurice Swinkels et al.
Scientific reports, 8(1), 1643-1643 (2018-01-28)
Retinal inflammation plays a key role in the progression of age-related macular degeneration (AMD), a condition that leads to loss of central vision. The deposition of the acute phase pentraxin C-reactive protein (CRP) in the macula activates the complement system
Anika Alberts et al.
Frontiers in immunology, 11, 596103-596103 (2020-12-29)
Endogenous and exogenous crystalline structures are involved in various pathologies and diseases in humans by inducing sterile inflammation, mechanical stress, or obstruction of excretory organs. The best studied of these diseases is gout, in which crystallization of uric acid in
Asmita Pathak et al.
Frontiers in immunology, 11, 1780-1780 (2020-08-28)
The aim of this study was to test the hypothesis that C-reactive protein (CRP) protects against the development of atherosclerosis and that a conformational alteration of wild-type CRP is necessary for CRP to do so. Atherosclerosis is an inflammatory cardiovascular
Anika Alberts et al.
Scientific reports, 10(1), 6391-6391 (2020-04-15)
Gout is caused by crystallization of uric acid in the form of monosodium urate (MSU) crystals, which induce a sterile inflammatory response that is hardly distinguishable from microbe-induced inflammatory responses. It is unclear, if MSU crystals (like microbes) are recognized
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