14-929-M

STK25, active

• UNSPSCコード: 12352204
• eCl@ss: 32160405
• NACRES: NA.32

特性

• 由来生物: human
• 品質水準: 100
• 分子量: M_w 63 kDa
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable (kinase)
• NCBIアクセッション番号: NM_006374
• UniProtアクセッション番号: O00506

詳細

詳細

Product Source: N-terminal GST-tagged and C-terminal 6His-tagged, recombinant, human STK25 amino acids 1-308, expressed by baculovirus in Sf21 insect cells

STK25 is a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18.

生物化学的／生理学的作用

Target Sub-Family: STE

包装

Also available in 250μg size as catalog # 14-929M and in bulk as catalog # 14-929-K.

品質

Routinely evaluated by phosphorylation of RLGRDKYKTLRQIRQ

物理的形状

Purified using glutathione sepharose.

50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol

保管および安定性

6 months at -70°C

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317
• 注意書き: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危険有害性の分類: Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable