14-1067

Human Recombinant MeCP2 (methyl-CpG-binding protein 2)

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells & purified by Fast Protein Liquid Chromatography (FPLC) & demonstrated to bind methylated DNA

• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

特性

• リコンビナント: expressed in Sf9 cells
• 品質水準: 100
• アッセイ: >95% (SDS-PAGE)
• 分子量: M_w 50.2 kDa (including histidine tag)
• 濃度: 0.5 μg/μL
• 輸送温度: dry ice

詳細

詳細

Human recombinant N-terminal His-tagged MeCP2 expressed in SF9 insect cells and purified by Fast Protein Liquid Chromatography (FPLC).

MeCP2 (methyl-CpG-binding protein 2) binds methylated CpG sequences in double-stranded DNA resulting in the suppression of transcription. This protein is likely to be involved in the repression of multiple genes. Consistent with this role, mutations of MeCP2 are linked to Rett syndrome, a progressive neurological disorder that is one of the most common causes of mental retardation in females.

アプリケーション

Research Category
エピジェネティクス及び核内機能分子

物理的形状

In a buffer containing 20 mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT.

保管および安定性

Stable at -80ºC for 6 months from date of receipt.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable