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アッセイ
≥95% (SDS-PAGE)
形状
solid
メーカー/製品名
Calbiochem®
保管条件
OK to freeze
不純物
≤5.0% Ash
≤6% moisture
pI
4.7
溶解性
water: 50 mg/mL
微量陽イオン
heavy metals: ≤20 ppm
輸送温度
ambient
保管温度
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI Key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
関連するカテゴリー
詳細
Human serum albumin (HSA) is an abundant protein found in the plasma. This globular, soluble, and unglycosylated monomeric protein, has three homologous domains (I, II, and III). These domains have subdomains A and B having common structural motifs. The HSA gene is located on the human chromosome 4q13.3.
アプリケーション
Albumin, Human Serum, Fraction V, Low Heavy Metals has been used:
- as a supplement in double buffer and milliQ-water for in vivo
- in serum-free media for polarized secretion assays in human dermal microvascular endothelial cells
- as a supplement in sodium phosphate buffer for the reconstitution of hormone lysis samples
生物化学的/生理学的作用
Human serum albumin (HSA) is very crucial in stabilizing extracellular fluid volume. It functions as an excipient for vaccines and therapeutic protein drugs. HSA serves as a cell culture medium supplement for the synthesis of vaccines and pharmaceuticals. It is useful as a carrier protein for steroids, fatty acids, and thyroid hormones. HSA is used to treat cardiopulmonary bypass, trauma, hemorrhage, and hypoalbuminemia. HSA is useful in biological applications, such as implantable biomaterials, biochromatography, surgical adhesives, and sealants.
警告
Toxicity: Standard Handling (A)
調製ノート
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
再構成
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
法的情報
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
12666-10GM:
12666-1GM:
12666-250GM:
12666-500GM:
12666-0GM:
12666-100GM:
12666-1KG:
12666-900GM:
12666-GM:
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
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The Journal of clinical endocrinology and metabolism, 104(12), 6403-6416 (2019-07-06)
After Roux-en-Y gastric bypass (RYGB) surgery, postprandial plasma glucagon concentrations have been reported to increase. This occurs despite concomitant improved glucose tolerance and increased circulating plasma concentrations of insulin and the glucagon-inhibiting hormone glucagon-like peptide 1 (GLP-1). To investigate whether
Journal of immunology (Baltimore, Md. : 1950), 170(5), 2647-2654 (2003-02-21)
Neutrophil chemotaxis is a critical component of the innate immune response. Neutrophils can sense an extremely shallow gradient of chemoattractants and produce relatively robust chemotactic behavior. This directional migration requires cell polarization with actin polymerization occurring predominantly in the leading
American journal of physiology. Endocrinology and metabolism, 311(2), E302-E309 (2016-06-02)
Glucagon is a metabolically important hormone, but many aspects of its physiology remain obscure, because glucagon secretion is difficult to measure in mice and rats due to methodological inadequacies. Here, we introduce and validate a low-volume, enzyme-linked immunosorbent glucagon assay
Molecules (Basel, Switzerland), 25(10) (2020-05-24)
Farnesoid X receptor (FXR) and Takeda G-protein coupled receptor 5 (TGR5) are the two known bile acid (BA) sensitive receptors and are expressed in the intestine and liver as well as in extra-enterohepatic tissues. The physiological effects of extra-enterohepatic FXR/TRG5
Antimicrobial agents and chemotherapy, 52(11), 3994-4000 (2008-09-10)
During antibiotic drug development, media are frequently spiked with either serum/plasma or protein supplements to evaluate the effect of protein binding. Usually, previously reported serum or plasma protein binding values are applied in the analysis. The aim of this study
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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