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Merck

1.05552

Supelco

TLC aluminum sheets, Cellulose

pkg of 25 sheets, sheet L × W 20 cm × 20 cm, aluminum support

別名:

Thin-layer chromatography cellulose plates

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About This Item

UNSPSCコード:
41115711
NACRES:
NB.21

物質

aluminum support
cellulose matrix

品質水準

特徴

binder Organic Polymer
fluorescent indicator: no

包装

pkg of 25 sheets

テクニック

thin layer chromatography (TLC): suitable

層厚

70-110 μm

シートL × W

20 cm × 20 cm

保管温度

2-30°C

詳細

25 Aluminium sheets 20 x 20 cm
Our cellulose plates are used to analyze polar substances. An organic sorbent, cellulose is perfect for separating hydrophilic substances by partition chromatography. Typical applications include the analysis of amino acids, carbohydrates, and phosphates as well as nucleic acid and nucleic acid derivatives. We offer cellulose plates in two grades: TLC for conventional and HPTLC for demanding, high-performance separations.

アプリケーション


  • Simple and sensitive determination of sulfites in Chinese herbal teas by ultrahigh-performance liquid chromatography tandem mass spectrometry: This study highlights the utilization of HILIC technology for the sensitive analysis of sulfites in herbal teas, demonstrating the versatility of SeQuant® ZIC-HILIC columns in maintaining the stability and enhancing the sensitivity of such measurements (Yang et al., 2022).

  • Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: The research applies HILIC methods to effectively measure antibiotics in various biological fluids, providing an example of the column′s applicability in pharmacokinetic research studies (Pandey et al., 2020).

  • Application of Hydrophilic Interaction Liquid Chromatography for the Quantification of Flavonoids in Genista tinctoria Extract: Demonstrates the use of HILIC for the effective separation and quantification of flavonoids, showcasing the column′s efficiency in handling complex herbal matrices (Sentkowska et al., 2016).

  • HPLC-UV method development for fentanyl determination in rat plasma and its application to elucidate pharmacokinetic behavior after i.p. administration to rats: This study underlines the adaptability of SeQuant® ZIC-HILIC in developing methods for the forensic and pharmacological analysis of potent opioids in biological samples (Almousa et al., 2011).

  • Hydrophilic interaction liquid chromatography/positive ion electrospray ionization mass spectrometry method for the quantification of perindopril and its main metabolite in human plasma: Highlights the application of HILIC in tandem with mass spectrometry for the analysis of drugs and their metabolites, emphasizing the column′s role in enhancing detection sensitivities (Georgakakou et al., 2010).

関連事項

Replaces: 5552-7; 5552

アナリシスノート

Layer thickness: 70 - 110 µm
Deviation of layer thickness per plate: ≤ 30 µm
Aminoacid test
hRf-values
- L-serine, amino acid test:
20 - 30
- L-threonine, amino acid test: 29 - 36
- L-alanine, amino acid test: 30 - 40
- L-methionine, amino acid test: 49 - 60
- L-phenylalanine, amino acid test: 59 - 70
- L-leucine, amino acid test: 66 - 76
Typical value determined on a sheet
Eluent: 1-Butanol/ acetone/ acetic acid/ water (35/35/7/23 v/v/v/v) twice developed

法的情報

SeQuant is a registered trademark of Merck KGaA, Darmstadt, Germany
ZIC-HILIC is a trademark of Merck KGaA, Darmstadt, Germany

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