07-1406
Anti-GLUT-5 Antibody, a.a. 490-502
serum, from rabbit
別名:
Fructose transporter, Glucose transporter type 5, small intestine, glucose transporter-like protein 5, solute carrier family 2 (facilitated glucose transporter),
member 5, solute carrier family 2 (facilitated glucose/fructose
transporte
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すべての画像(3)
About This Item
UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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由来生物
rabbit
品質水準
抗体製品の状態
serum
抗体製品タイプ
primary antibodies
クローン
polyclonal
化学種の反応性
rat, guinea pig, mouse
テクニック
western blot: suitable
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
mouse ... Slc2A5(56485)
詳細
A cytochalasin B-sensitive carrier located in the membrane, GLUT-5 appears to be primarily functional as a fructose transporter. It is expressed in the small intestine, and is also found in the skeletal muscle, kidney and adipose tissue but at significantly reduced levels.
特異性
Recognizes GLUT-5.
免疫原
Epitope: C-terminus
Synthetic peptide corresponding to the C-terminus of rat GLUT-5 (aa 490-502) coupled to KLH. The immunogen sequence used is only 53% conserved in mouse.
アプリケーション
Research Category
細胞シグナル伝達
細胞シグナル伝達
Research Sub Category
インスリン/エネルギーシグナル伝達
インスリン/エネルギーシグナル伝達
Anti-GLUT-5 Antibody, a.a. 490-502 detects level of GLUT-5 & has been published & validated for use in WB.
品質
Evaluated by Western Blot in Mouse kidney lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.
Western Blot Analysis: A 1:1000 dilution of this antibody detected GLUT-5 in 10 µg of mouse kidney lysates.
ターゲットの説明
Approx. 54 kDa
関連事項
Replaces: AB1348
物理的形状
Unpurified rabbit serum
Liquid containing 0.05% sodium azide.
保管および安定性
Store at -20°C in undiluted aliquots for up to 1 year from date of receipt. Avoid repeated freeze-thaw cycles.
アナリシスノート
Control
Mouse kidney lysate.
Mouse kidney lysate.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
07-1406:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.
Irene Zwarts et al.
Scientific reports, 9(1), 9299-9299 (2019-06-28)
Fructose has become a major constituent of our modern diet and is implicated as an underlying cause in the development of metabolic diseases. The fructose transporter GLUT5 (SLC2A5) is required for intestinal fructose absorption. GLUT5 expression is induced in the
High Fructose Corn Syrup Accelerates Kidney Disease and Mortality in Obese Mice with Metabolic Syndrome.
Andres-Hernando, et al.
Biomolecules, 13 (2023)
Ana Andres-Hernando et al.
Cell metabolism, 32(1), 117-127 (2020-06-06)
Intake of fructose-containing sugars is strongly associated with metabolic syndrome. Compared with other sugars, dietary fructose is uniquely metabolized by fructokinase. However, the tissue-specific role of fructokinase in sugar-induced metabolic syndrome, and the specific roles of glucose and fructose in
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