04-959

Anti-Retinoid-Related Orphan Receptor γ T Antibody, clone RORg2

clone RORg2, from hamster(Armenian)

• 別名: RAR-related orphan receptor C, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, nuclear receptor ROR-gamma, retinoid-related orphan receptor gamma, Nuclear receptor RZR-gamma, RZR-GAMMA, Nuclear receptor subfamily 1 group F member
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: hamster (Armenian)
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: RORg2, monoclonal
• 化学種の反応性: mouse
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_035411
• UniProtアクセッション番号: P51450
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Rorc(19885)

詳細

詳細

Retinoid-related orphan receptor-gamma t (RORγT) is one of two RORγ isoforms belonging to the nuclear hormone receptor family and contains a single nuclear receptor DNA-binding domain. RORγT is a negative regulator of TNFDF6/FASL expression and T-cell production of IL2. The upregulation of RORγT is a requirement for TH17 cell differentiation. Inhibition of RORγT is induced by TGF-β’s interaction with Foxp3. Expression is observed mainly in immature thymocytes, and, during fetal development, is found exclusively in lymphoid-inducer (LTi) cells.

免疫原

Epitope: Unknown

Histidine-tagged recombinant protein corresponding to mouse Retinoid-Related Orphan Receptor γ T (RORγT).

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
炎症及び自己免疫疾患

Detect Retinoid-Related Orphan Receptor γ T using this Anti-Retinoid-Related Orphan Receptor γ T Antibody, clone RORg2 validated for use in WB, FC & IF.

品質

Evaluated by Western Blot in EL4 cell lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected Retinoid-Related Orphan Receptor γ T (RORγT) in 10 µg of EL4 cell lysate.

ターゲットの説明

~52 kDa observed

物理的形状

Protein G Purified

Format: Purified

Purified hamster monoclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
EL4 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable