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Merck

810600C

Avanti

16:0-12 Doxyl PC

Avanti Research - A Croda Brand 810600C

別名:

1-palmitoyl-2-stearoyl-(12-doxyl)-sn-glycero-3-phosphocholine

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About This Item

実験式(ヒル表記法):
C46H90N2O10P
CAS番号:
分子量:
862.19
UNSPSCコード:
51321705
NACRES:
NA.25

アッセイ

>99% (TLC)

フォーム

liquid

包装

pkg of 1 × 1 mL (810600C-1mg)

メーカー/製品名

Avanti Research - A Croda Brand 810600C

濃度

1 mg/mL (810600C-1mg)

脂質タイプ

phospholipids
ESR probes

輸送温度

dry ice

保管温度

−20°C

詳細

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

包装

5 mL Clear Glass Sealed Ampule (810600C-1mg)

調製ノート

To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM.,Supplemental information

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

ピクトグラム

Skull and crossbonesHealth hazard

シグナルワード

Danger

危険有害性の分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

ターゲットの組織

Central nervous system

保管分類コード

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

引火点(°F)

does not flash

引火点(℃)

does not flash


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

PRTR

第一種指定化学物質

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

810600C-VAR:
810600C-BULK:
810600C-1MG:


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試験成績書(COA)

Lot/Batch Number

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Kervin O Evans et al.
Biochimica et biophysica acta, 1848(5), 1175-1182 (2015-02-18)
The phenols hydroxytyrosol and tyrosol made abundantly available through olive oil processing were enzymatically transesterified into effective lipophilic antioxidants with cuphea oil. The hydroxytyrosyl and tyrosyl esters made from cuphea oil were assessed for their ability to partition into, locate
Ling Yan et al.
FEBS letters, 555(3), 545-550 (2003-12-17)
We investigated the ability of tBid (truncated form of Bid) to bind and permeabilize the liposomes (large unilamellar vesicles, LUVs) and release fluorescent marker molecules (fluorescein-isothiocyanate-conjugated dextrans, FITC-dextrans) of various molecular diameters (FD-20, FD-70, FD-250S) from LUVs. Obtained data showed
L A Falls et al.
The Journal of biological chemistry, 276(26), 23895-23902 (2001-04-20)
The hydrophobic omega-loop within the prothrombin gamma-carboxyglutamic acid-rich (Gla) domain is important in membrane binding. The role of this region in membrane binding was investigated using a synthetic peptide, PT-(1-46)F4W, which includes the N-terminal 46 residues of human prothrombin with
Local polarity and hydrogen bonding inside the Sec14p phospholipid-binding cavity: high-field multi-frequency electron paramagnetic resonance studies.
Smirnova TI, et al.
Biophysical Journal, 92, 3686-3695 (2007)
H H de Jongh et al.
Biochimica et biophysica acta, 1024(1), 82-88 (1990-05-09)
Bacteriophage M13 major coat protein was spin-labeled with a nitroxide derivative of iodoacetamide, preferentially at the single methionine that is located in the hydrophobic region of the protein. The spin-labeled protein was incorporated at different lipid-to-protein ratios in phospholipid bilayers

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