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Owing to their plasmonic properties nanoparticles of gold and silver find broad range of applications extending from diagnostics to molecular detection, photothermal and microwave-based therapies, and nanotoxicology. Colloidal silver nanoparticles also find applications in antimicrobial coatings, electronics and photovoltaics, and surface enhanced Raman spectroscopy (SERS) whereas the colloidal gold nanoparticles find applications in lateral flow assays (immunochromatographic assays) and as TEM labels and size standards.
The BioReady gold nanospheres are well suited for passive conjugation of antibodies, proteins, peptides, and other biomolecules.
The BioReady citrate gold nanoparticles have a “naked” particle surface which contains a weakly bound citrate molecule as stabilizer. The citrate is readily displaced in presence of proteins and allows passive adsorption (also referred to as physisorption). The mechanism of adsorption is based on Van der Waals interactions between the proteins (e.g. antibodies) and the surface of the particles. The resulting forces between the antibody and the nanoparticle are influenced by the coupling environment. Our BioReady citrate gold is provided at an optical density (OD) of 20 at pH ~8.0–8.5. A pH titration should be performed to optimize the pH of conjugation.
The BioReady carbonate gold nanoparticles have a “naked” particle surface that contains a weakly bound carbonate molecule as particle stabilizer and, similar to citrate-stabilized gold, the carbonate is readily displaced in the presence of proteins and allows easy passive adsorption. Carbonate is a smaller and less complex molecule and has a lower affinity to the gold nanoparticle surface compared to citrate. This enhances the displaceability of the carbonate molecules allows better conjugation. Our BioReady carbonate gold is provided at an optical density (OD) of 20 at pH ~7.4–8.6. A pH titration should be performed to optimize the pH of conjugation.
The BioReady gold nanospheres are well suited for passive conjugation of antibodies, proteins, peptides, and other biomolecules.
The BioReady citrate gold nanoparticles have a “naked” particle surface which contains a weakly bound citrate molecule as stabilizer. The citrate is readily displaced in presence of proteins and allows passive adsorption (also referred to as physisorption). The mechanism of adsorption is based on Van der Waals interactions between the proteins (e.g. antibodies) and the surface of the particles. The resulting forces between the antibody and the nanoparticle are influenced by the coupling environment. Our BioReady citrate gold is provided at an optical density (OD) of 20 at pH ~8.0–8.5. A pH titration should be performed to optimize the pH of conjugation.
The BioReady carbonate gold nanoparticles have a “naked” particle surface that contains a weakly bound carbonate molecule as particle stabilizer and, similar to citrate-stabilized gold, the carbonate is readily displaced in the presence of proteins and allows easy passive adsorption. Carbonate is a smaller and less complex molecule and has a lower affinity to the gold nanoparticle surface compared to citrate. This enhances the displaceability of the carbonate molecules allows better conjugation. Our BioReady carbonate gold is provided at an optical density (OD) of 20 at pH ~7.4–8.6. A pH titration should be performed to optimize the pH of conjugation.
保管および安定性
DO NOT FREEZE. Store at 2-8C and away from light when not in use to maximize shelf life. Nanomaterials can be sensitive to high and low pH conditions and high salt concentrations. Use caution when changing environmental conditions as particles may aggregate.
法的情報
Product of nanoComposix, Inc.
保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
NCXAUCR40-100ML:
NCXAUCR40-5ML:
NCXAUCR40-30ML:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
関連コンテンツ
抗体に含まれるフリーのアミノ基と金ナノ粒子表面上のカルボン酸とのアミド結合によって抗体を共有結合させる方法について解説しました。
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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