551007

クロロギ酸2,7-ジ-tert-ブチル-9-フルオレニルメチル

97%

• 化学式: ClCOOCH₂CH(C₆H₃C(CH₃)₃)₂
• CAS番号: 287381-46-8
• 分子量: 370.91
• MDL番号: MFCD03701519
• UNSPSCコード: 12352100
• PubChem Substance ID: 24879152

特性

• アッセイ: 97%
• mp: 66-70 °C (lit.)
• 保管温度: 2-8°C
• SMILES記法: CC(C)(C)c1ccc-2c(c1)C(COC(Cl)=O)c3cc(ccc-23)C(C)(C)C
• InChI: 1S/C23H27ClO2/c1-22(2,3)14-7-9-16-17-10-8-15(23(4,5)6)12-19(17)20(18(16)11-14)13-26-21(24)25/h7-12,20H,13H2,1-6H3
• InChI Key: PHUMWWRUIGKGNN-UHFFFAOYSA-N

詳細

詳細

2,7-Di-tert-butyl-9-fluorenylmethyl chloroformate contains 2,7-di-tert-butyl-Fmoc protecting group (Fmoc= fluorenylmethoxycarbonyl), which is more soluble in organic solvents when compared to its Fmoc analog. It can be prepared from fluorene in three steps, by di-tert-butylation, hydroxymethylation and phosgenation.

アプリケーション

2,7-Di-tert-butyl-9-fluorenylmethyl chloroformate may be used in the preparation of polymer-supported (2,7-di-tert-butyl-9-fluorenyl)methyl succinimidyl carbonate (Dtb-Fmoc-P-OSu), a polymeric reagent for protecting amino groups.

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Danger
• 危険有害性情報: H314
• 注意書き: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• 危険有害性の分類: Skin Corr. 1B
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges