498327

2-フルオロアセト酢酸エチル

• 別名: 2-Fluoro-3-oxobutanoic acid ethyl ester, Ethyl 2-fluoro-3-oxobutanoate, Ethyl 2-fluoro-3-oxobutyrate, NSC 24563
• 化学式: CH₃COCH(F)CO₂C₂H₅
• CAS番号: 1522-41-4
• 分子量: 148.13
• MDL番号: MFCD00215830
• UNSPSCコード: 12352100
• PubChem Substance ID: 24873190

特性

• 屈折率: n20/D 1.414 (lit.)
• bp: 183 °C (lit.)
• 密度: 1.181 g/mL at 25 °C (lit.)
• SMILES記法: CCOC(=O)C(F)C(C)=O
• InChI: 1S/C6H9FO3/c1-3-10-6(9)5(7)4(2)8/h5H,3H2,1-2H3
• InChI Key: SHTFQLHOTAJQRJ-UHFFFAOYSA-N

詳細

詳細

Ethyl 2-fluoroacetoacetate is an α-fluorinated β-keto ester that can be prepared by the fluorination of ethyl acetoacetate.

アプリケーション

Ethyl 2-fluoroacetoacetate may be used in the preparation of:

• δ-keto-β-hydroxy-α-fluoro esters
• fluorinated [1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-ones
• fluorinated [1,2,4]triazolo[5,1-c][1,2,4]triazin-4(1H)-ones
• 4-fluorofarnesol

Reactant for:

• Michael addition-induced cyclization reaction
• Asymmetric Mannich reaction
• Enantioselective organocatalytic conjugate addition

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): 194.0 °F - closed cup
• 引火点(℃): 90 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves, type ABEK (EN14387) respirator filter