372714

2,6-Dimethoxypyridine-3-carboxylic acid

99%

• 別名: 2,6-Dimethoxynicotinic acid
• 実験式（ヒル表記法）: C₈H₉NO₄
• CAS番号: 16727-43-8
• 分子量: 183.16
• MDL番号: MFCD00075582
• UNSPSCコード: 12352100
• PubChem Substance ID: 24863158

特性

• アッセイ: 99%
• mp: 140-144 °C (lit.)
• SMILES記法: COc1ccc(C(O)=O)c(OC)n1
• InChI: 1S/C8H9NO4/c1-12-6-4-3-5(8(10)11)7(9-6)13-2/h3-4H,1-2H3,(H,10,11)
• InChI Key: SDJQZCSCHUIITF-UHFFFAOYSA-N

詳細

詳細

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) is a piperidine derivative. It forms various organotin(IV) complexes and their antiproliferative action against pancreatic carcinoma (PANC-1), erythroleukemia (K562), and two glioblastoma multiform (U87 and LN-229) human cell lines has been evaluated.

アプリケーション

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-Dimethoxynicotinic acid, DMNIH) may be used in the preparation of the following organotin(IV) complexes (DMNIH=2,6-dimethoxynicotinic acid, BZDOH=1,4-benzodioxane-6-carboxylic acid, DMFUH=2,5-dimethyl-3-furoic acid and Cy=cyclohexyl):

• [SnCy₃-(DMNI)]
• [SnCy₃(BZDO)]
• [SnCy₃(DMFU)]
• [SnPh₂-(BZDO)₂]

2,6-Dimethoxypyridine-3-carboxylic acid (2,6-dimethoxynicotinic acid, DMPH) may be used in the preparation of novel benzothiazolo naphthyridone carboxylic acid derivatives. It may be used in the preparation of following complexes, via reaction with different precursors [Ti(η⁵-C₅H₅)₂Cl₂], [Ti(η⁵-C₅H₄Me)₂Cl₂], [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)Cl₂], [Ti(η⁵-C₅Me₅)Cl₃], SnMe₃Cl and GatBu₃:

• [Ti(η⁵-C₅H₅)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄Me)₂(DMP-κO)₂]
• [Ti(η⁵-C₅H₄SiMe₃)(η⁵-C₅H₅)(DMP-κO)₂
• [Ti(η⁵-C₅Me₅)(DMP-κ²O,O′)₃]
• [SnMe₃(μ-DMP-κO:κO′)]_∞
• [GatBu₂(μ-DMP-κO:κO′)]₂

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319,H335
• 注意書き: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves