アッセイ
97%
SMILES記法
ClC(Cl)C(=O)NCCCCCCCCNC(=O)C(Cl)Cl
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 2
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
147508-1G:
147508-VAR:
147508-BULK:
最新バージョンのいずれかを選択してください：
K Momma et al.
Fetal diagnosis and therapy, 9(1), 44-52 (1994-01-01)
Interrupted aortic arch type B associated with ventricular septal defect (n = 17) or atrioventricular septal defect (n = 2) was induced in 19 of 300 fetuses by maternal administration of bis-diamine on the 9th and 10th day of pregnancy.
John K Amory et al.
Journal of andrology, 32(1), 111-119 (2010-08-14)
The bisdichloroacetyldiamine WIN 18,446 reversibly inhibits spermatogenesis in many species, including humans; however, the mechanism by which WIN 18,446 functions is unknown. As retinoic acid is essential for spermatogenesis, we hypothesized that WIN 18,446 might inhibit retinoic acid biosynthesis from
H Tasaka et al.
Teratology, 43(3), 191-200 (1991-03-01)
Administration of N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine, bisdiamine, in pregnant Donryu rats on day 10 of gestation induces a high incidence of cardiovascular anomalies in fetuses. Bisdiamine administration induced aplasia of the sixth aortic arch artery, with both the right and left primitive pulmonary
M Jackson et al.
Cardiovascular research, 30(6), 992-1000 (1995-12-01)
To examine morphological similarities between "classically different" congenital heart lesion types induced in fetal rats by the cardiac teratogen N,N'-bis(dichloroacetyl)-1,8-octamethylenediamine (bis-diamine). A single 200 mg oral dose of bis-diamine was given to 50 pregnant rats on the 9th gestational day.
Takashi Hanato et al.
Birth defects research. Part B, Developmental and reproductive toxicology, 92(1), 10-16 (2011-02-12)
Conotruncal anomalies are often associated with abnormal coronary arteries. Although bis-diamine is known to induce conotruncal defects, its pathological effects on coronary vascular development have not been demonstrated. This study sought to assess the teratogenic effects of bis-diamine on coronary
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