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Merck

TRPV4

transient receptor potential cation channel, subfamily V, member 4

別名:
CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VRL2, VROAC
Species:
UniProtKB ID:
遺伝子ID:
  • Human(59341) Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
  • Mouse(63873) transient receptor potential cation channel, subfamily V, member 4
  • Rat(66026) transient receptor potential cation channel, subfamily V, member 4
  • naked mole-rat(101706710) transient receptor potential cation channel, subfamily V, member 4
  • domestic guinea pig(100724607) transient receptor potential cation channel, subfamily V, member 4
  • sheep(101113534) transient receptor potential cation channel, subfamily V, member 4
  • domestic cat(101084907) transient receptor potential cation channel, subfamily V, member 4
  • Horse(100066552) transient receptor potential cation channel, subfamily V, member 4
  • cow(540259) transient receptor potential cation channel, subfamily V, member 4
  • chicken(395427) transient receptor potential cation channel, subfamily V, member 4
  • dog(486308) transient receptor potential cation channel, subfamily V, member 4
  • Zebrafish(557850) transient receptor potential cation channel, subfamily V, member 4

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Small Molecule - Agonist

製品番号
詳細
Species
ジヒドロカプサイシン, from Capsicum sp., ≥85%,
Species
rat, human
N-バニリルノナンアミド, ≥97%, powder,
Species
rat

Small Molecule - Antagonist

製品番号
詳細
Species
カプサゼピン, ≥98% (HPLC), solid,
Species
human, rat
カプサイシン, ≥95%, from Capsicum sp.,
Species
rat, human
カプサイシン, natural,
Species
rat, human
カプサイシン, from Capsicum sp., ≥50% (HPLC),
Species
rat, human
2,2′:5′,2″:5″,2″′-クアテルチオフェン, 96%,
Species
human, rat, mouse

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-TRPV4 Antibody, clone 1G10-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
canine, human, mouse, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-Trpv4 Antibody, clone 1B2.6, clone 1B2.6, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
western blot
抗TRPV4 ウサギ宿主抗体, affinity isolated antibody, lyophilized powder,
交差性
rat
アプリケーション
western blot
Anti-Transient Receptor Potential Vanilloid 4 Antibody, pain, Chemicon®, from rabbit,
交差性
rat
アプリケーション
western blot
抗TRPV4抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
human, rabbit
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
Butamben, United States Pharmacopeia (USP) Reference Standard,
Species
human
カプサイシン, ≥95%, from Capsicum sp.,
Species
rat, human
カプサイシン, natural,
Species
rat, human
カプサイシン, from Capsicum sp., ≥50% (HPLC),
Species
rat, human
2,2′:5′,2″:5″,2″′-クアテルチオフェン, 96%,
Species
human, rat, mouse

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
N-バニリルノナンアミド, ≥97%, powder,
Species
rat
カプサゼピン, ≥98% (HPLC), solid,
Species
human, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Trpv4,
Species
mouse
MISSION® esiRNA, targeting human TRPV4,
Species
human