コンテンツへスキップ
Merck

SOCS1

suppressor of cytokine signaling 1

別名:
CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(8651) Summary: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
  • Mouse(12703) suppressor of cytokine signaling 1
  • Rat(252971) suppressor of cytokine signaling 1
  • naked mole-rat(101729320) suppressor of cytokine signaling 1
  • domestic guinea pig(100728652) suppressor of cytokine signaling 1
  • cow(518795) suppressor of cytokine signaling 1
  • sheep(101107324) suppressor of cytokine signaling 1
  • dog(490006) suppressor of cytokine signaling 1
  • chicken(416630) suppressor of cytokine signaling 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
抗SOCS1抗体 ウサギ宿主抗体, IgG fraction of antiserum,
交差性
bovine, human, mouse, pig, rabbit, rat
アプリケーション
immunohistochemistry
western blot
抗SOCS1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-SOCS1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
抗SOCS1抗体、クローン4H1, clone 4H1, Upstate®, from mouse,
交差性
human, mouse
アプリケーション
immunoprecipitation (IP)
western blot
Anti-SOCS1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human SOCS1,
Species
human
MISSION® esiRNA, targeting mouse Socs1,
Species
mouse