SMAD4
SMAD family member 4
別名:
DPC4, JIP, MADH4, MYHRS
Species:
Human SMAD4 (4089), Mouse Smad4 (17128), Rat Smad4 (50554), dog SMAD4 (476196), domestic cat SMAD4 (101093650), Zebrafish smad4 (30640), domestic guinea pig Smad4 (100717853), naked mole-rat Smad4 (101703764), sheep SMAD4 (443171), cow SMAD4 (540248) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(4089) Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
- Mouse(17128) SMAD family member 4
- Rat(50554) SMAD family member 4
- dog(476196) SMAD family member 4
- domestic cat(101093650) SMAD family member 4
- Zebrafish(30640) MAD homolog 4 (Drosophila)
- domestic guinea pig(100717853) SMAD family member 4
- naked mole-rat(101703764) SMAD family member 4
- sheep(443171) SMAD family member 4
- cow(540248) SMAD family member 4
- Horse(100033846) SMAD family member 4
- Goat(100861019) SMAD family member 4
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ELISA
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
抗SMAD4抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse
アプリケーション
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-SMAD4 antibody produced in mouse, clone 4G1C6, ascites fluid,
交差性
human
アプリケーション
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-SMAD4 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM277, purified immunoglobulin,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
抗SMAD4抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
アプリケーション
immunohistochemistry
western blot
western blot
Anti-Smad4/DPC4 Antibody, from rabbit, purified by affinity chromatography,
交差性
chimpanzee, human, mouse, rat
アプリケーション
immunocytochemistry
western blot
western blot
Cell Lines
Proteins
製品番号
詳細
Species
SMAD4、GSTタグ融合 ヒト, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human