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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

別名:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

製品番号
詳細
Species
Human COX-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
交差性
mouse
アプリケーション
immunohistochemistry
western blot
抗COX2 ウサギ宿主抗体, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-Cox2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
交差性
human
アプリケーション
immunohistochemistry

Small Molecule - Blocker

製品番号
詳細
Species
N-p-トシル-L-フェニルアラニンクロロメチルケトン, ≥97% (TLC), powder,
Species
human

Small Molecule - Inhibitor

製品番号
詳細
Species
カルプロフェン, ≥97% (HPLC),
Species
human
アセクロフェナク, ≥98% (HPLC),
Species
human
セレコキシブ, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
セレコキシブ, United States Pharmacopeia (USP) Reference Standard,
Species
human
エトリコキシブ, VETRANAL®, analytical standard,
Species
human

Proteins

製品番号
詳細
Species
シクロオキシゲナーゼ2 ヒト, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Ptgs2,
Species
mouse
MISSION® esiRNA, targeting human PTGS2,
Species
human