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Merck

PRKAA1

protein kinase, AMP-activated, alpha 1 catalytic subunit

別名:
AMPK, AMPKa1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5562) Summary: The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(105787) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Rat(65248) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Horse(100009710) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(100294665) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • dog(479351) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic guinea pig(100714483) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • Zebrafish(100001198) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • chicken(427185) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • cow(540404) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • naked mole-rat(101722998) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • sheep(101103425) protein kinase, AMP-activated, alpha 1 catalytic subunit
  • domestic cat(101095885) protein kinase, AMP-activated, alpha 1 catalytic subunit

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-AMPK α (Thr172) Antibody, Upstate®, from rabbit,
交差性
human, rat
アプリケーション
western blot
抗リン酸化AMPKα-1抗体(Thr479), from rabbit, purified by affinity chromatography,
交差性
bovine, horse, human, mouse, porcine, rat
アプリケーション
dot blot
western blot
抗AMPK 抗体 クローン2D22 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
Anti-AMPK α-pan Antibody, Upstate®, from rabbit,
交差性
human, rat
アプリケーション
western blot
Anti-AMPK alpha 1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot

Proteins

製品番号
詳細
Species
AMPK(A1/B1/G1)、活性型、Hisタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK(A1/B1/G3), 活性型, Hisタグ付加 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
AMPK(A1/B2/G1), 活性型, Hisタグ付加 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PRKAA1,
Species
human
MISSION® esiRNA, targeting mouse Prkaa1,
Species
mouse