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Merck

PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

別名:
PLA2G4, cPLA2-alpha
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5321) Summary: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. [provided by RefSeq, Jul 2008]
  • Mouse(18783) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Rat(24653) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • dog(480048) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Horse(100033889) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • cow(525072) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • Zebrafish(559087) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • domestic guinea pig(100715719) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • domestic cat(101082033) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • chicken(396394) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • sheep(101111472) phospholipase A2, group IVA (cytosolic, calcium-dependent)
  • naked mole-rat(101704061) phospholipase A2, group IVA (cytosolic, calcium-dependent)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-c-PLA2 (pSer505) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-C-PLA2 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PLA2G4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-PLA2G4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-cPLA2 Antibody, clone 2F4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
affinity binding assay
immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PLA2G4A,
Species
human
MISSION® esiRNA, targeting mouse Pla2g4a,
Species
mouse