MECP2
methyl CpG binding protein 2 (Rett syndrome)
別名:
AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
Species:
Human MECP2 (4204), Mouse Mecp2 (17257), Rat Mecp2 (29386), domestic cat MECP2 (101082385), Zebrafish mecp2 (335250), Domestic Rabbit MECP2 (100328751), dog MECP2 (612973), domestic guinea pig Mecp2 (100734864), sheep MECP2 (101121154), naked mole-rat Mecp2 (101700584)
UniProtKB ID:
遺伝子ID:
- Human(4204) Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009]
- Mouse(17257) methyl CpG binding protein 2
- Rat(29386) methyl CpG binding protein 2
- domestic cat(101082385) methyl CpG binding protein 2 (Rett syndrome)
- Zebrafish(335250) methyl CpG binding protein 2
- Domestic Rabbit(100328751) methyl CpG binding protein 2 (Rett syndrome)
- dog(612973) methyl CpG binding protein 2 (Rett syndrome)
- domestic guinea pig(100734864) methyl CpG binding protein 2 (Rett syndrome)
- sheep(101121154) methyl CpG binding protein 2 (Rett syndrome)
- naked mole-rat(101700584) methyl CpG binding protein 2 (Rett syndrome)
- cow(539629) methyl CpG binding protein 2 (Rett syndrome)
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Antibodies
製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-MECP2 antibody produced in mouse, clone 4B6, purified immunoglobulin, buffered aqueous solution,
交差性
mouse
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-MeCP2, from rabbit, purified by affinity chromatography,
交差性
bovine, human, mouse, rat, rhesus macaque
アプリケーション
immunofluorescence
western blot
western blot
抗MECP2抗体 ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
immunohistochemistry
Monoclonal Anti-MECP2 antibody produced in mouse, clone 1B11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗MECP2抗体 ウサギ宿主抗体, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Proteins
製品番号
詳細
Species