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Merck

MAP2K6

mitogen-activated protein kinase kinase 6

別名:
MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5608) Summary: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]
  • Mouse(26399) mitogen-activated protein kinase kinase 6
  • Rat(114495) mitogen-activated protein kinase kinase 6
  • dog(480454) mitogen-activated protein kinase kinase 6
  • chicken(417445) mitogen-activated protein kinase kinase 6
  • Zebrafish(65239) mitogen-activated protein kinase kinase 6
  • domestic guinea pig(100731419) mitogen-activated protein kinase kinase 6
  • naked mole-rat(101703028) mitogen-activated protein kinase kinase 6
  • sheep(101115047) mitogen-activated protein kinase kinase 6
  • Domestic Rabbit(100355230) mitogen-activated protein kinase kinase 6
  • cow(286883) mitogen-activated protein kinase kinase 6
  • domestic cat(101089813) mitogen-activated protein kinase kinase 6
  • Horse(100053056) mitogen-activated protein kinase kinase 6

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MAP2K6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
SAPK Pathway Explorer Antibody Minipack, Upstate®,
交差性
アプリケーション
Monoclonal Anti-MAP2K6 antibody produced in mouse, clone 2F2, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-MKK6 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-MAP2K6 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
PD 98,059, solid,
Species
human

Proteins

製品番号
詳細
Species
MKK6 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE),
Species
human
MKK6/SKK3 Protein, active, 10 µg, Active, N-terminal, maltose binding protein tagged, human MKK6/SKK3 fusion protein, amino acids 4-end. For use in Kinase Assays.,
Species
human
MKK6/SKK3, active human, ≥80% (SDS-PAGE), recombinant, expressed in E. coli, Maltose binding protein tagged, buffered aqueous solution,
Species
human
MKK6/SKK3 Protein, inactive, 50 g, Unactive, recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag, for use in Kinase Assays.,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® Long Non-Coding esiRNA, targeting human MAP2K6,
Species
human
MISSION® esiRNA, targeting mouse Map2k6,
Species
mouse