HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
別名:
DFNB39, F-TCF, HGFB, HPTA, SF
Species:
Human HGF (3082), Mouse Hgf (15234), Rat Hgf (24446), cow HGF (282879), sheep HGF (443075), Domestic Rabbit HGF (100316908), domestic guinea pig Hgf (100730730), naked mole-rat Hgf (101707056), chicken HGF (395941), dog HGF (403441)
UniProtKB ID:
遺伝子ID:
- Human(3082) Summary: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(15234) hepatocyte growth factor
- Rat(24446) hepatocyte growth factor
- cow(282879) hepatocyte growth factor (hepapoietin A; scatter factor)
- sheep(443075) hepatocyte growth factor (hepapoietin A; scatter factor)
- Domestic Rabbit(100316908) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic guinea pig(100730730) hepatocyte growth factor (hepapoietin A; scatter factor)
- naked mole-rat(101707056) hepatocyte growth factor (hepapoietin A; scatter factor)
- chicken(395941) hepatocyte growth factor (hepapoietin A; scatter factor)
- dog(403441) hepatocyte growth factor (hepapoietin A; scatter factor)
- domestic cat(493705) hepatocyte growth factor (hepapoietin A; scatter factor)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
抗HGF抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, horse, human, mouse, pig, rabbit, rat
アプリケーション
western blot
抗HGF抗体(ab2) ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
アプリケーション
immunohistochemistry
western blot
western blot
抗HGF抗体 ウサギ宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse
アプリケーション
proximity ligation assay
western blot
western blot
抗HGF抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-Hepatocyte Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
Proteins
製品番号
詳細
Species
肝細胞増殖因子 ヒト, HGF, recombinant, expressed in Baculovirus infected High-5 cells, suitable for cell culture,
Species
human
HGF mouse, recombinant, expressed in Hi-5 Insect cells, ≥95% (SDS-PAGE), ≥95% (HPLC),
Species
mouse