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Merck

EIF2AK2

eukaryotic translation initiation factor 2-alpha kinase 2

別名:
EIF2AK1, PKR, PRKR
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5610) Summary: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(19106) eukaryotic translation initiation factor 2-alpha kinase 2
  • Rat(54287) eukaryotic translation initiation factor 2-alpha kinase 2
  • Zebrafish(100001092) eukaryotic translation initiation factor 2-alpha kinase 2
  • domestic guinea pig(100717384) eukaryotic translation initiation factor 2-alpha kinase 2
  • Domestic Rabbit(100009013) eukaryotic translation initiation factor 2-alpha kinase 2
  • domestic cat(101082744) eukaryotic translation initiation factor 2-alpha kinase 2
  • sheep(101121673) eukaryotic translation initiation factor 2-alpha kinase 2
  • dog(611397) eukaryotic translation initiation factor 2-alpha kinase 2
  • naked mole-rat(101724844) eukaryotic translation initiation factor 2-alpha kinase 2
  • Horse(100147679) eukaryotic translation initiation factor 2-alpha kinase 2
  • chicken(395147) eukaryotic translation initiation factor 2-alpha kinase 2
  • cow(347700) eukaryotic translation initiation factor 2-alpha kinase 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-phospho-PKR (pThr446) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
抗PKR抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Phospho-PKR/EIF2AK2-T446 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-PKR Antibody, clone 2H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, rat
アプリケーション
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-PKR (Thr446) Antibody, Upstate®, from rabbit,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Eif2ak2,
Species
mouse
MISSION® esiRNA, targeting human EIF2AK2,
Species
human