SAB4300222

Anti-phospho-EIF2AK2 (pThr⁴⁴⁶) antibody produced in rabbit

affinity isolated antibody

• 別名: 抗EIF2AK1抗体 ウサギ宿主抗体, 抗MGC126524抗体 ウサギ宿主抗体, 抗PKR抗体 ウサギ宿主抗体, 抗PRKR抗体 ウサギ宿主抗体
• MDL番号: MFCD03455796
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: ~74 kDa
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (K-R-TP-R-S)
• NCBIアクセッション番号: NP_001129123.1
• UniProtアクセッション番号: P19525
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pThr446)
• 遺伝子情報: human ... EIF2AK2(5610)

詳細

免疫原

Peptide sequence around phosphorylation site of threonine 446 (K-R-T(p)-R-S), according to the protein EIF2AK2.

特徴および利点

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ターゲットの説明

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable