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Merck

DIABLO

diablo, IAP-binding mitochondrial protein

別名:
DFNA64, SMAC
Species:
Human DIABLO (56616), Mouse Diablo (66593), Rat Diablo (288753), chicken DIABLO (416860), cow DIABLO (493999), domestic guinea pig Diablo (100724526), naked mole-rat Diablo (101708166), sheep DIABLO (101121971), dog DIABLO (477463)
UniProtKB ID:
Q9NR28, B2RDQ0, Q6W3F3, Q96LV0, Q9BT11, Q9HAV6
遺伝子ID:
  • Human(56616) Summary: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Mouse(66593) diablo homolog (Drosophila)
  • Rat(288753) diablo, IAP-binding mitochondrial protein
  • chicken(416860) diablo, IAP-binding mitochondrial protein
  • cow(493999) diablo, IAP-binding mitochondrial protein
  • domestic guinea pig(100724526) diablo, IAP-binding mitochondrial protein
  • naked mole-rat(101708166) diablo, IAP-binding mitochondrial protein
  • sheep(101121971) diablo, IAP-binding mitochondrial protein
  • dog(477463) diablo, IAP-binding mitochondrial protein

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ELISA

製品番号
詳細
Species
RAB0841
Mouse Diablo / Diablo Homolog, Mitochondrial ELISA Kit, ,
Species
mouse
RAB0912
Rat DIABLO / Diablo Homolog (Drosophila) ELISA Kit, ,
Species
rat

Antibodies

製品番号
詳細
交差性
アプリケーション
PRS2411
Anti-SMAC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5701661
Anti-Smac/Diablo antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
ZRB2891
Anti-Smac/DIABLO Antibody, clone 2B9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human
アプリケーション
flow cytometry
immunocytochemistry
western blot
HPA001825
Anti-DIABLO antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
SAB3500327
Anti-Smac antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot

esiRNA

製品番号
詳細
Species
EHU145751
MISSION® esiRNA, targeting human DIABLO, RP11-512M8.5,
Species
human
EMU067981
MISSION® esiRNA, targeting mouse Diablo,
Species
mouse