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Merck

COL25A1

collagen, type XXV, alpha 1

別名:
AMY, CLAC, CLAC-P, CLACP
Species:
UniProtKB ID:
遺伝子ID:
  • Human(84570) Summary: This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  • Mouse(77018) collagen, type XXV, alpha 1
  • Rat(687064) collagen, type XXV, alpha 1
  • dog(610442) collagen, type XXV, alpha 1
  • domestic cat(101089352) collagen, type XXV, alpha 1
  • chicken(429900) collagen, type XXV, alpha 1
  • domestic guinea pig(100717264) collagen, type XXV, alpha 1
  • naked mole-rat(101706837) collagen, type XXV, alpha 1
  • Horse(100072894) collagen, type XXV, alpha 1
  • cow(615661) collagen, type XXV, alpha 1
  • sheep(101120576) collagen, type XXV, alpha 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗COL25A1 ウサギ宿主抗体, affinity isolated antibody,
交差性
dog, human
アプリケーション
western blot
Anti-Collagen XXV α1 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
western blot
抗COL25A1抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Monoclonal Anti-COL25A1 antibody produced in mouse, clone 1D2, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human COL25A1,
Species
human