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Merck

CARD8

caspase recruitment domain family, member 8

別名:
CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN
Species:
Human CARD8 (22900), dog CARD8 (491519), domestic cat CARD8 (101093817), chicken CARD8 (416998)
UniProtKB ID:
Q9Y2G2, B5KVR6, B7Z496, B7Z4A2, E9PEM7, G3XAM9, Q6PGP8, Q96P82
遺伝子ID:
  • Human(22900) Summary: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
  • dog(491519) caspase recruitment domain family, member 8
  • domestic cat(101093817) caspase recruitment domain family, member 8
  • chicken(416998) caspase recruitment domain family, member 8

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA043513
抗CARD8抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
HPA042071
抗CARD8抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
western blot
ZRB2636
Anti-CARD8 Antibody, clone 1C23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
EHU070091
MISSION® esiRNA, targeting human CARD8,
Species
human

Small Molecule - Substrate

製品番号
詳細
Species
A4188
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human
A9968
N-アセチル-Ile-Glu-Thr-Asp-p-ニトロアニリド, ≥95%,
Species
rat, mouse, human
A6470
N-Acetyl-Ile-Glu-Pro-Asp-p-nitroanilide, ≥97% (HPLC), powder,
Species
rat, mouse, human
A6220
N-アセチル-Ile-Glu-Pro-Asp-7-アミド-4-メチルクマリン, ≥97% (HPLC), powder,
Species
rat, mouse, human