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Merck

BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

別名:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
Species:
UniProtKB ID:
遺伝子ID:
  • Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
  • Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)

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ELISA

製品番号
詳細
Species
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-BMR2 Antibody, clone 3F6, ascites fluid, clone 3F6, from mouse,
交差性
human, monkey, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
交差性
human, monkey, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 4A2, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA

Proteins

製品番号
詳細
Species
BMPR2 (174-end)、活性型、、Hisタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human BMPR2,
Species
human
MISSION® esiRNA, targeting mouse Bmpr2,
Species
mouse