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Safety Information

T0178

Sigma-Aldrich

apo-Transferrin bovine

≥98%

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About This Item

CAS Number:
11096-37-0
EC Number:
234-318-8
MDL number:
MFCD00130536
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

bovine

Assay

≥98%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 20 mg/mL

UniProt accession no.

Q29443

storage temp.

2-8°C

Gene Information

bovine ... TF(280705)

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Application

All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

2020135:
T0178-VAR:
T0178-500MG:
T0178-100MG:
T0178-BULK:
T0178-50MG:

Certificates of Analysis (COA)

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Sandeep Kumar et al.
The journal of physical chemistry. B, 121(37), 8669-8683 (2017-08-25)
The macromolecular crowding influences the structural stability and functional properties of transferrin (Tf). The equilibrium as well as kinetic studies of Tf at different concentrations of crowding agents (dextran 40, dextran 70, and ficoll 70) and at a fixed concentration
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