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Safety Information

S4311

Sigma-Aldrich

L-Serine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

Synonym(s):

L Serine, (S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
56-45-1
Molecular Weight:
105.09
Beilstein:
1721404
EC Number:
200-274-3
MDL number:
MFCD00064224
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24899599
NACRES:
NA.26

product name

L-Serine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

biological source

non-animal source

Agency

USP/NF
meets EP testing specifications
meets USP testing specifications

Assay

98.5-101.0%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

application(s)

pharmaceutical (small molecule)

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

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Application

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.
Precursor of glycine by serine hydroxymethyltransferase.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

2550079:
2519042:
S4311-25G:
S4311-BULK:
S4311-100G:
S4311-VAR:
S4311-1KG:
S4311-25KG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Miyoshi Haruta et al.
Science (New York, N.Y.), 343(6169), 408-411 (2014-01-25)
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