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Safety Information

I9386

Sigma-Aldrich

myo-Inositol 1,3,4,6-tetrakis-phosphate ammonium salt

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About This Item

Empirical Formula (Hill Notation):
C6H16O18P4 · xNH3
CAS Number:
142507-74-2
Molecular Weight:
500.08 (free acid basis)
UNSPSC Code:
12352201
PubChem Substance ID:
24896156

storage temp.

−20°C

SMILES string

N.O[C@H]1[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O

InChI

1S/C6H16O18P4.H3N/c7-1-3(21-25(9,10)11)5(23-27(15,16)17)2(8)6(24-28(18,19)20)4(1)22-26(12,13)14;/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);1H3/t1-,2+,3-,4+,5-,6+;

InChI key

ANQVRWQIKKBLLK-PWRMZBPBSA-N

Biochem/physiol Actions

Accumulates with angiotensin II stimulation; stimulates intracellular Ca++ release.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

I9386-VAR:
I9386-50UG:
I9386-.1MG:
I9386-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
SLBL3061V
SLBD1044V
090M1369
049K1124
108K1606

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T Balla et al.
Biochemical and biophysical research communications, 148(1), 199-205 (1987-10-14)
Angiotensin II stimulates the formation of several inositol polyphosphates in cultured bovine adrenal glomerulosa cells prelabelled with [3H] inositol. Analysis by high performance anion exchange chromatography of the inositol-phosphate compounds revealed the existence of two additional inositol tetrakisphosphate (InsP4) isomers
D J Gawler et al.
The Biochemical journal, 276 ( Pt 1), 163-167 (1991-05-15)
The potential Ca2(+)-releasing activity of the inositol tetrakisphosphates Ins(1,3,4,6)P4 and DL-Ins(1,4,5,6)P4 and the inositol pentakisphosphate Ins(1,3,4,5,6)P5 and their effect on Ins(1,4,5)P3- and DL-Ins (1,3,4,5)P4-mediated Ca2+ release were examined in permeabilized SH-SY5Y human neuroblastoma cells. Neither DL-Ins(1,4,5,6)P4 nor Ins(1,3,4,5,6)P5 exhibit Ca2(+)-releasing

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