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F0537

Sigma-Aldrich

Fusicoccin from Fusicoccum amygdali

≥85% (HPLC)

Synonym(s):

Fusicoccin A

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1 MG
¥77,800

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1 MG
¥77,800

About This Item

Empirical Formula (Hill Notation):
C36H56O12
CAS Number:
20108-30-9
Molecular Weight:
680.82
MDL number:
MFCD00070322
UNSPSC Code:
12352201
PubChem Substance ID:
24894726
NACRES:
NA.25

¥77,800

Available to ship onApril 09, 2025Details

Request a Bulk Order

biological source

plant (Fusicoccum amygdali)

Quality Level

200

Assay

≥85% (HPLC)

form

solid

storage temp.

−20°C

SMILES string

COCC1CCC2C(C)C(O)C(OC3OC(COC(C)(C)C=C)C(O)C(OC(C)=O)C3O)C4=C(CC(O)C4(C)C=C12)C(C)COC(C)=O

InChI

1S/C36H56O12/c1-10-35(6,7)45-17-26-30(41)33(46-21(5)38)31(42)34(47-26)48-32-28-24(18(2)15-44-20(4)37)13-27(39)36(28,8)14-25-22(16-43-9)11-12-23(25)19(3)29(32)40/h10,14,18-19,22-23,26-27,29-34,39-42H,1,11-13,15-17H2,2-9H3/b25-14-

InChI key

KXTYBXCEQOANSX-QFEZKATASA-N

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Application

Fusicoccin (Fusicoccin A), a diterpene glucoside phytotoxin, is used to study 14-3-3-dependent processes such as the activation of H+-ATPase in plants and other client proteins with mode III binding motifs.[1] Fusicoccin is an inducer of a catalase inhibitor that leads to oxidative damage in plants.[2]

Other Notes

A diterpene glucoside with numerous physiological effects on plants.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

F0537-VAR:
F0537-1MG-PW:
F0537-PPG:
F0537-PH:
F0537-BULK:
F0537-250UG:
F0537-250UG-PW:
F0537-1MG:
F0537PROC:

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Certificates of Analysis (COA)

Lot/Batch Number
0000415003
0000415003
0000368430
0000280199
0000362163

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A H de Boer
Biochemical Society transactions, 30(4), 416-421 (2002-08-28)
Turgor pressure is a cellular parameter, important for a range of physiological processes in plants, like cell elongation, gas exchange and gravitropic/phototropic bending. Regulation of turgor pressure involves ion and water transport at the expense of metabolic energy (ATP). The
Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions.
Rolf Rose et al.
Angewandte Chemie (International ed. in English), 49(24), 4129-4132 (2010-05-04)
Yusuke Ono et al.
Journal of the American Chemical Society, 133(8), 2548-2555 (2011-02-09)
Fusicoccin A and cotylenin A are structurally related diterpene glucosides and show a phytohormone-like activity. However, only cotylenin A induces the differentiation of human myeloid leukemia cells. Since the cotylenin A producer lost its ability to proliferate during preservation, a
Ingrid J de Vries-van Leeuwen et al.
Cancer letters, 293(2), 198-206 (2010-02-16)
Active small molecules have a high potential for the development into new anti-cancer drugs. Here we analysed the effect of the natural occurring fusicoccanes, Fusicoccin-A (FC), Ophiobolin-A (OPH-A) and Ophiobolin-I (OPH-I) on various tumor cell lines. Both FC and OPH-A
L Baunsgaard et al.
The Plant journal : for cell and molecular biology, 13(5), 661-671 (1998-07-29)
The plasma membrane H(+)-ATPase in higher plants has been implicated in nutrient uptake, phloem loading, elongation growth and establishment of turgor. Although a C-terminal regulatory domain has been identified, little is known about the physiological factors involved in controlling the
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