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C2605

Sigma-Aldrich

Cellulase from Aspergillus sp.

greener alternative

aqueous solution

Synonym(s):

Carezyme 4500L®, Carezyme®

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About This Item

CAS Number:
9012-54-8
Enzyme Commission number:
3.2.1.4 (BRENDA, IUBMB)
EC Number:
232-734-4
MDL number:
MFCD00081510
UNSPSC Code:
12352204
NACRES:
NA.54

form

solid

specific activity

≥1000 units/g

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

greener alternative category

Enabling,

storage temp.

2-8°C

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency and waste prevention when used in cellulosic ethanol research. For more information see the article in biofiles and Enzymes for Alternative Energy Research

Application

Cellulase from Aspergillus sp. has been used to degrade cello-oligosaccharides into glucose during the analysis of BBC (bioabsorbable bacterial cellulose) biodegradability. The enzyme has also been used in photon correlation spectroscopy to study its effects on unfiltered beer samples. The parameters evaluated in this spectroscopic analysis were the size of suspended particles, flow rate and haze stability.

Biochem/physiol Actions

Cellulases are enzymes that hydrolyze cellulose, a linear polymer of anhydroglucose units linked together by β-1,4-glycosidic bonds, to glucose. Endo-β-D-glucanase is one of the major component enzymes of the cellulase complex. It catalyzes the hydrolysis of cellulose by randomly splitting the sugar residues within the molecule. Exo-β-D-glucanase and β-glucosidase can synergistically convert cellulose into glucose and hence are used on an industrial scale.

Preparation Note

produced by submerged fermentation of a genetically modified Aspergillus microorganism

Other Notes

View more information on enzymes for complex carbohydrate analysis at www.sigma-aldrich.com/enzymeexplorer

Legal Information

A product of Novozyme Corp.
Carezyme is a registered trademark of Novozymes Corp.

Pictograms

Health hazard
GHS08

Signal Word

Danger

Hazard Statements

H334

Hazard Classifications

Resp. Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

C2605-VAR:
C2605-50ML:
C2605-250ML:
C2605-BULK:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Monitoring of Beer Filtration Using Photon Correlation Spectroscopy (PCS).
Sensidoni M, et al.
Journal of the Institute of Brewing, 117(4), 639-646 (2011)
Pierre-Louis Bombeck et al.
Biotechnology for biofuels, 10, 293-293 (2017-12-12)
Lignocellulosic biomass will progressively become the main source of carbon for a number of products as the Earth's oil reservoirs disappear. Technology for conversion of wood fiber into bioproducts (wood biorefining) continues to flourish, and access to reliable methods for
Muhammad Sohail et al.
New biotechnology, 25(6), 437-441 (2009-06-26)
Fungal cellulases are well-studied enzymes and are used in various industrial processes. Much of the knowledge of enzymatic depolymerization of cellulosic material has come from Trichoderma cellulase system. Species of Trichoderma can produce substantial amounts of endoglucanase and exoglucanase but
Yang Hu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 97(1), 114-123 (2011-02-04)
Cellulose biodegradation resulting from enzymolysis generally occurs in nature rather than in the human body because of the absence of cellulose degrading enzymes. In order to achieve in-vivo degradation in human body for in-vivo tissue regeneration applications, we developed a
Akihiko Nakamura et al.
Journal of synchrotron radiation, 20(Pt 6), 859-863 (2013-10-15)
Neutron protein crystallography (NPC) is a powerful tool for determining the hydrogen position and water orientation in proteins, but a much larger protein crystal is needed for NPC than for X-ray crystallography, and thus crystal preparation is a bottleneck. To
View All Related Papers

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