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R7635

Supelco

Ronidazole

analytical standard

Synonym(s):

1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C6H8N4O4
CAS Number:
7681-76-7
Molecular Weight:
200.15
EC Number:
231-675-1
MDL number:
MFCD00133801
UNSPSC Code:
41116107
PubChem Substance ID:
329823648
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥95%

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

−20°C

SMILES string

Cn1c(COC(N)=O)ncc1N(=O)=O

InChI

1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)

InChI key

PQFRTXSWDXZRRS-UHFFFAOYSA-N

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General description

Ronidazole is a nitroimidazole compound, commonly used as antiprotozoal and antibacterial agent.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ronidazole may be used as a reference standard in the determination of the analyte in poultry muscle and eggs using high-performance liquid chromatography with ultraviolet detection and confirmatory analysis by atmospheric pressure chemical ionization-mass spectrometry.

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

R7635-VAR:
R7635-100G:
R7635-25G:
R7635-BULK:
R7635-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT7186
MKCS7829
MKCS3424
MKCM1762
MKCH9347

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Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry.
Sams JM, et al.
Analyst, 123(1-2), 2545-2549 (1998)
Neurotoxicosis in 4 cats receiving ronidazole.
Terri W Rosado et al.
Journal of veterinary internal medicine, 21(2), 328-331 (2007-04-13)
J L Gookin et al.
Journal of veterinary internal medicine, 24(4), 1003-1007 (2010-05-25)
The mainstays of treatment for clinically important trichomonad infections are the 5-nitroimidazoles. Metronidazole resistance of feline Tritrichomonas foetus is presumed because of common treatment failure, and tinidazole does not consistently eradicate infection. To date, ronidazole is the only drug demonstrated
Malcolm Holliday et al.
Journal of feline medicine and surgery, 11(2), 131-134 (2008-09-09)
Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smears (n=20) and T foetus-specific culture (n=74), with confirmation
Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.
Hoffer Max and Grunberg E
Journal of Medicinal Chemistry, 17(9), 1019-1020 (1974)
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