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P1240000

Phenylephrine

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

L-Phenylephrine

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About This Item

Empirical Formula (Hill Notation):
C9H13NO2
CAS Number:
59-42-7
Molecular Weight:
167.21
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

phenylephrine

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m0/s1

InChI key

SONNWYBIRXJNDC-VIFPVBQESA-N

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Phenylephrine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Phenylephrine bitartrate, United States Pharmacopeia (USP) Reference Standard

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Phenylephrine Related Compound C, United States Pharmacopeia (USP) Reference Standard

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Phenylephrine Related Compound F, United States Pharmacopeia (USP) Reference Standard

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Phenylephrine Related Compound G, United States Pharmacopeia (USP) Reference Standard

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PHR2153

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PHR2151

1,2,3,4-Tetrahydro-4,6-dihydroxy-2-methylisoquinoline hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2148

Phenylephrine Related Compound D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2154

N-Formylphenylephrine, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2149

Phenylephrine Related Compound F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2150

Phenylephrine Related Compound G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR3221

Phenylephrine Bitartrate, pharmaceutical secondary standard, certified reference material

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

P1240000-1EA:
P1240000:

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Certificates of Analysis (COA)

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A G Tahiliani et al.
General pharmacology, 13(5), 369-374 (1982-01-01)
To summarize, a large number of studies indicate that the effects of phenylephrine on cardiac contractility are mediated through alpha-adrenoceptors, although not exclusively. There are an equally large number of reports indicating some beta-adrenoceptor stimulant effects of phenylephrine. Of the
Ashraf S Habib
Anesthesia and analgesia, 114(2), 377-390 (2011-11-23)
Phenylephrine is effective for the management of spinal anesthesia-induced hypotension in parturients undergoing cesarean delivery under spinal anesthesia. While ephedrine was previously considered the vasopressor of choice in obstetric patients, phenylephrine is increasingly being used. This is largely due to
Hartley C Atkinson et al.
European journal of clinical pharmacology, 71(2), 151-158 (2014-12-06)
Over-the-counter combinations containing acetaminophen and phenylephrine for treatment of the common cold and influenza are widespread, but there are few data about pharmacokinetics of these two drugs used in combination. We aimed to investigate pharmacokinetic interactions between acetaminophen and phenylephrine.
Joseph R H Mauban et al.
American journal of physiology. Heart and circulatory physiology, 307(2), H173-H181 (2014-05-27)
We used two-photon (2-p) Förster resonance energy transfer (FRET) microscopy to provide serial, noninvasive measurements of [Ca(2+)] in arterioles of living "biosensor" mice. These express a genetically encoded Ca(2+) indicator (GECI), either FRET-based exMLCK or intensity-based GCaMP2. The FRET ratios
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