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MAB885

Sigma-Aldrich

Anti-Papillomavirus Antibody, 16L1, late protein, clone Cam Vir-1

clone Cam Vir-1, Chemicon®, from mouse

Synonym(s):

HPV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

300

antibody form

purified antibody

antibody product type

primary antibodies

clone

Cam Vir-1, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2a

shipped in

wet ice

Specificity

L1 (late) protein of Human Papilloma Virus type 16. Useful for studies of HPV in cervical smears and biopsies. Recognizes HPV-16 L1 by immunoprecipitation, western blotting and immunofluorescence on cells fixed in acetone or paraformaldehyde and immunoperoxidase staining of paraffin sections.

Immunogen

Beta galactosidase-HPV L1 fusion protein containing the c-terminal 60% of the L1 sequence.
Epitope: 16L1, Late Protein

Application

Anti-Papillomavirus Antibody, 16L1, late protein, clone Cam Vir-1 detects level of Papillomavirus & has been published & validated for use in IP, WB, IH(P).
Immunoprecipitation, western blotting and immunofluorescence.

Immunohistochemistry.

Shows reactivity on fixed tissue. Dilute with buffer pH 7.5 -8.0 to desired working volumes. For extensive dilution, protein containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Physical form

Format: Purified
Liquid in phosphate buffer saline (PBS), pH 7.4 with 0.1% sodium azide.

Storage and Stability

Maintain at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB885:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Seroprevalence of seven high-risk HPV types in The Netherlands.
Mirte Scherpenisse,Madelief Mollers,Rutger M Schepp,Hein J Boot,Hester E de Melker et al.
Vaccine null
Xue Chen et al.
Human vaccines & immunotherapeutics, 14(8), 2025-2033 (2018-04-24)
Current available human papillomavirus (HPV) vaccines are based on the major capsid protein L1 virus-like particles (VLPs), which mainly induce type-specific neutralizing antibodies against vaccine types. Continuing to add more types of VLPs in a vaccine raises the complexity and
Valeria Russo et al.
Pathogens (Basel, Switzerland), 9(4) (2020-04-09)
Multiple papillomatous nodules were observed scattered over the amniotic membrane in six water buffaloes that had recently aborted. Grossly, some of the nodules had multiple villous projections while others appeared as single prominent conical or cylindrical horns. Histology revealed folded
Analysis of the L1 gene product of human papillomavirus type 16 by expression in a vaccinia virus recombinant.
Browne, H M, et al.
The Journal of General Virology, 69 ( Pt 6), 1263-1273 (1988)
Mingrao Ma et al.
Frontiers in bioengineering and biotechnology, 10, 1073892-1073892 (2023-01-24)
Human papillomavirus (HPV) major capsid protein L1 virus-like particles (VLPs) produced in the baculovirus system showed excellent safety and immunogenicity, but the relatively high production cost stands as a substantial barrier to extensive commercialization, especially in producing multivalent vaccines. Here
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