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MAB8679

Sigma-Aldrich

Anti-Papillomavirus Antibody, 2-17, clone TVG 261

clone TVG 261, Chemicon®, from mouse

Synonym(s):

HPV 16 E2

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

300

antibody form

purified immunoglobulin

clone

TVG 261, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG1

shipped in

wet ice

General description

The HPV family of DNA tumor viruses includes HPV-16 and is associated with a large portion of cervical cancer cases.

Specificity

HPV-16-E2, aa 2-17 of human papilloma virus type 16-E2. ETLCQRLNVCQDKILT

Immunogen

Epitope: 2-17
Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).

Application

Anti-Papillomavirus Antibody, 2-17, clone TVG 261 detects level of Papillomavirus & has been published & validated for use in ELISA & WB.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Western Blot

ELISA

Optimal dilutions must be determined by end user

Physical form

Format: Purified
Purified immunoglobulin. Liquid 0.02M PB, 0.25M NaCl, pH 7.6 buffer containing 0.1% sodium azide as a preservative.

Storage and Stability

Store at 2 to 8°C for up to 12 months from date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

MAB8679:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Hibma, M H, et al.
European Journal of Biochemistry, 229, 517-525 (1995)
E Z Tchilian et al.
Journal of immunology (Baltimore, Md. : 1950), 166(2), 1308-1313 (2001-01-06)
SCID is a heterogeneous group of hereditary diseases. Mutations in the common gamma-chain (gamma(c)) of cytokine receptors, including those for IL-2, IL-4, IL-7, IL-9, and IL-15, are responsible for an X-linked form of the disease, while mutations of several other
Martha Luevano et al.
Virology, 405(1), 31-40 (2010-06-18)
We have developed microarrays with all eight proteins encoded by 13 different human papillomavirus types associated with anogenital cancer (HPV-16, -18, -31, -33, -35, -45, and -53), genital warts (HPV-6 and -11), or skin lesions (HPV-1, -2, -4, and -5).

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