Skip to Content
Merck
All Photos(1)

Documents

Safety Information

520224

Sigma-Aldrich

PPACK, Dihydrochloride, Biotinylated

Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Synonym(s):

PPACK, Dihydrochloride, Biotinylated, Biotin-X-D-Phe-Pro-Arg-chloromethylketone, 2HCl

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C43H70ClN10O7S · 2HCl
Molecular Weight:
979.52
UNSPSC Code:
12352200

Quality Level

100

Assay

≥80% (HPLC and TLC)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

General description

Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no
Target IC50: 110 nM against thrombin

Warning

Toxicity: Standard Handling (A)

Physical form

In 10 mM HCl.

Other Notes

Williams, E.B., et al. 1989. J. Biol. Chem.264, 7536.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

JAN Code

520224-MG:
520224-1MG:

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service